The best Side of cees dekker

The best Side of cees dekker

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Human Rad51 filaments on double- and one-stranded DNA: correlating typical and irregular varieties with recombination perform.

Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I

Our operate was immediately adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors made from single- and multi-walled carbon nanotubes in Used Physics Letters.

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During the decades following these discoveries, my investigate pursuits shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The focus of numerous scientists in the sector also shifted to graphene (exactly where, funnily enough, the main graphene ribbons ended up referred to as ‘nanotubes which are cut open up alongside their length’) just after the discovery of the two-dimensional product in 2004.

Length control of person carbon nanotubes by nanostructuring Using the scanning tunneling microscope

Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation

In 1993, being a youthful and keen associate professor at Delft University of Know-how, I'd initially targeted the exploration endeavours of my group on measuring the electrical conductance of just one conducting-polymer molecule. In two decades, we had produced a device through which only one wire of the phthalocyaninepolysiloxane polymer was related in between two closely spaced steel nanoelectrodes.

There was 1 difficulty even though — we did not observe any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule degree, conducting polymers have been in fact not these good conductors, which was alternatively disappointing. We So broadened our perspective to test to uncover extra promising molecules.

‘The concept there is such a point for a commencing, a big bang, is currently an interesting signpost to take into account that there was a creator. But additional frequently, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview is actually a naturalistic worldview: basically, you can find only atoms and pure forces that we can easily evaluate.

‘That fears the synthetic cell, as Element of the Dutch BaSyC initiative. Craig Venter looked prime-down in those days and determined about 5 hundred genes which are minimally expected for a working mobile. We wish to look bottom-up: how can we shift from a number of molecules ceesdekker.net to an entire biological method?

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes

Good-point out nanopores have tested to generally be a incredibly adaptable probe for solitary-molecule Examination of DNA. I will describe some of our recent conclusions – specially DNA knots – together with our initiatives to grow the capabilities of strong-state nanopores even further, during the way of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.